AOD-9604 vs Semaglutide
Which should you choose? Here's what you need to know.
The short answer
Semaglutide is FDA-approved with strong clinical evidence for significant weight loss. AOD-9604 is a growth hormone fragment studied for fat metabolism, but it has not shown consistent weight loss results in human trials.
On 9 Oct 2026 Peptide Compare tracked 53 vendors selling AOD-9604, cheapest in stock $5.00 per mg at LA Peptides, and 29 selling Semaglutide, cheapest $1.83 per mg at Modern Research.
AOD-9604
Weight Loss (GLP-1)AOD-9604 is a synthetic fragment of human growth hormone (amino acids 177-191) that's been studied for its effects on fat metabolism. It's researched for stimulating fat breakdown and inhibiting fat creation without affecting blood sugar or growth.
Choose AOD-9604 if:
You want a peptide studied specifically for fat metabolism without appetite suppression, or you can't tolerate GLP-1 side effects like nausea.
Semaglutide
Weight Loss (GLP-1)Semaglutide is the active ingredient in Ozempic and Wegovy — an FDA-approved GLP-1 receptor agonist with extensive clinical data. The STEP 1 trial showed an average of 14.9% body weight loss over 68 weeks. It works by reducing appetite, slowing digestion, and improving insulin sensitivity.
Choose Semaglutide if:
You want a clinically proven, FDA-approved option with the strongest weight loss evidence available.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Oct 9, 2026.
AOD-9604
Semaglutide
$25.00
Starting from
$24.99
$10.31
Avg. price per mg
$25.64
53
Vendors selling it
29
46 options
In stock now
59 options
9.1/10
Top trust score
8.7/10
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.