AOD-9604 vs Semaglutide
Which should you choose? Here's what you need to know.
The short answer
Semaglutide is FDA-approved with strong clinical evidence for significant weight loss. AOD-9604 is a growth hormone fragment studied for fat metabolism, but it has not shown consistent weight loss results in human trials.
AOD-9604
Weight Loss (GLP-1)AOD-9604 is a synthetic fragment of human growth hormone (amino acids 177-191) that's been studied for its effects on fat metabolism. It's researched for stimulating fat breakdown and inhibiting fat creation without affecting blood sugar or growth.
Choose AOD-9604 if:
You want a peptide studied specifically for fat metabolism without appetite suppression, or you can't tolerate GLP-1 side effects like nausea.
Semaglutide
Weight Loss (GLP-1)Semaglutide is the active ingredient in Ozempic and Wegovy — an FDA-approved GLP-1 receptor agonist with extensive clinical data. The STEP 1 trial showed an average of 14.9% body weight loss over 68 weeks. It works by reducing appetite, slowing digestion, and improving insulin sensitivity.
Choose Semaglutide if:
You want a clinically proven, FDA-approved option with the strongest weight loss evidence available.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
Best AOD-9604 Vendor
$29.99(5mg)
Best Semaglutide Vendor
$165.00(20mg)
Where does this data come from?
We check vendor prices every day and pull in real purity test results from independent labs — not vendor claims. No vendor can pay to rank higher. See our full methodology.