IGF-1 LR3 vs Sermorelin
Which should you choose? Here's what you need to know.
The short answer
Sermorelin gently stimulates your body's natural GH production. IGF-1 LR3 bypasses GH entirely for direct, potent growth factor delivery. Very different risk and reward profiles.
On 9 Oct 2026 Peptide Compare tracked 46 vendors selling IGF-1 LR3, cheapest in stock $20.83 per mg at Bio Pepz, and 46 selling Sermorelin, cheapest $3.84 per mg at Bio Pepz.
IGF-1 LR3
Growth HormoneIGF-1 LR3 is a long-acting synthetic growth factor approximately 2.5x more potent than natural IGF-1. It directly stimulates muscle protein synthesis and cell proliferation without going through the GH pathway.
Choose IGF-1 LR3 if:
You want the most direct growth factor stimulation possible and accept the higher risk profile of a potent research compound.
Sermorelin
Growth HormoneSermorelin is a well-established GHRH analog that mimics your body's natural GH-releasing hormone. It produces gentle, physiological GH pulses and has decades of clinical use.
Choose Sermorelin if:
You prefer a gentle, natural approach to raising GH — especially for anti-aging, sleep, and long-term wellness.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Oct 9, 2026.
IGF-1 LR3
Sermorelin
$12.00
Starting from
$22.00
$164.45
Avg. price per mg
$9.51
46
Vendors selling it
46
40 options
In stock now
54 options
9.1/10
Top trust score
9.0/10
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Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.