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HomePeptidesAOD-9604 vs Retatrutide

AOD-9604 vs Retatrutide

Which should you choose? Here's what you need to know.

The short answer

Retatrutide is the most effective weight loss peptide in trials. AOD-9604 is a GH fragment studied for fat metabolism that never proved effective in human trials — dramatically different evidence levels.

On 9 Oct 2026 Peptide Compare tracked 53 vendors selling AOD-9604, cheapest in stock $5.00 per mg at LA Peptides, and 31 selling Retatrutide, cheapest $2.20 per mg at Modern Research.

AOD-9604

Weight Loss (GLP-1)

AOD-9604 is a synthetic fragment of growth hormone studied for fat metabolism. Despite completing six human trials, the largest Phase IIb trial did not reach statistical significance and development was terminated in 2007.

Choose AOD-9604 if:

You want a peptide focused on fat metabolism without appetite suppression, though evidence of effectiveness is weak.

Retatrutide

Weight Loss (GLP-1)

Retatrutide is a triple receptor agonist showing 28.7% mean weight loss in Phase 3 trials — the highest ever recorded for an obesity drug. It hits GLP-1, GIP, and glucagon pathways simultaneously.

Choose Retatrutide if:

You want maximum weight loss backed by strong clinical trial data.

Price & availability

Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Oct 9, 2026.

AOD-9604
Retatrutide
$25.00
Starting from
$25.99
$10.31
Avg. price per mg
$10.03
53
Vendors selling it
31
46 options
In stock now
98 options
9.1/10
Top trust score
9.0/10

Ready to buy?

Our top-rated vendor for each, based on trust scores, purity testing, and price.

Some outbound links may earn us a commission. Vendors cannot pay to improve rankings.

Best AOD-9604 Vendor

Eros Peptides
Eros Peptides
6.9/10

$49.99(10mg)

Check Price

Best Retatrutide Vendor

Polaris Peptides
Polaris Peptides
7.3/10

$400.00(60mg)

Check Price
See all AOD-9604 vendorsSee all Retatrutide vendorsBest AOD-9604 vendors, rankedBest Retatrutide vendors, ranked

Where does this data come from?

We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.