Cagrilintide vs Tirzepatide
Which should you choose? Here's what you need to know.
The short answer
Cagrilintide works through the amylin system (appetite and satiety), while tirzepatide is a dual GIP/GLP-1 agonist. Tirzepatide is FDA-approved; cagrilintide is still in trials but shows strong results — especially combined with semaglutide as CagriSema.
On 9 Oct 2026 Peptide Compare tracked 38 vendors selling Cagrilintide, cheapest in stock $4.50 per mg at Amino Sequence, and 30 selling Tirzepatide, cheapest $1.76 per mg at Modern Research.
Cagrilintide
Weight Loss (GLP-1)Cagrilintide is a long-acting amylin receptor agonist that mimics the satiety hormone amylin. It's being studied for weight management and is the amylin half of Novo Nordisk's CagriSema combination, which showed over 20% weight loss in the REDEFINE 1 trial. On its own, cagrilintide has a notably lower rate of nausea than most GLP-1-based options.
Choose Cagrilintide if:
You're interested in a different mechanism than GLP-1 agonists, want to avoid severe nausea, or are looking at next-generation combination approaches like CagriSema.
Tirzepatide
Weight Loss (GLP-1)Tirzepatide (Mounjaro/Zepbound) is a dual GIP and GLP-1 receptor agonist that's already FDA-approved for both type 2 diabetes and weight management. Clinical trials demonstrated up to 22.5% body weight reduction, making it one of the most effective single-agent weight loss peptides available today.
Choose Tirzepatide if:
You want an FDA-approved, clinically proven option with extensive real-world data and strong weight loss results right now.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Oct 9, 2026.
Cagrilintide
Tirzepatide
$32.58
Starting from
$30.95
$16.32
Avg. price per mg
$9.04
38
Vendors selling it
30
41 options
In stock now
100 options
9.0/10
Top trust score
9.0/10
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.