Cagrilintide vs Tirzepatide
Which should you choose? Here's what you need to know.
The short answer
Cagrilintide works through the amylin system (appetite and satiety), while tirzepatide is a dual GIP/GLP-1 agonist. Tirzepatide is FDA-approved; cagrilintide is still in trials but shows strong results — especially combined with semaglutide as CagriSema.
Cagrilintide
Weight Loss (GLP-1)Cagrilintide is a long-acting amylin receptor agonist that mimics the satiety hormone amylin. It's being studied for weight management and is the amylin half of Novo Nordisk's CagriSema combination, which showed over 20% weight loss in the REDEFINE 1 trial. On its own, cagrilintide has a notably lower rate of nausea than most GLP-1-based options.
Choose Cagrilintide if:
You're interested in a different mechanism than GLP-1 agonists, want to avoid severe nausea, or are looking at next-generation combination approaches like CagriSema.
Tirzepatide
Weight Loss (GLP-1)Tirzepatide (Mounjaro/Zepbound) is a dual GIP and GLP-1 receptor agonist that's already FDA-approved for both type 2 diabetes and weight management. Clinical trials demonstrated up to 22.5% body weight reduction, making it one of the most effective single-agent weight loss peptides available today.
Choose Tirzepatide if:
You want an FDA-approved, clinically proven option with extensive real-world data and strong weight loss results right now.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Cagrilintide
Tirzepatide
$29.99
Starting from
$22.99
$16.84
Avg. price per mg
$6.51
43
Vendors selling it
34
50 options
In stock now
110 options
9.0/10
Top trust score
9.0/10
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.