peptide-compare.com

FOXO4-DRI vs MOTS-c

Which should you choose? Here's what you need to know.

The short answer

FOXO4-DRI and MOTS-c are both metabolic / longevity peptides, but they work differently. A D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells. A mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism. Compare vendor pricing and availability below.

FOXO4-DRI

Metabolic / Longevity

A D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells.

MOTS-c

Metabolic / Longevity

A mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism.

Price & availability

Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.

FOXO4-DRI
MOTS-c
$98.00
Starting from
$29.99
$24.67
Avg. price per mg
$5.67
14
Vendors selling it
60
14 options
In stock now
61 options
9.0/10
Top trust score
9.0/10
0
Purity tests on file
0

Ready to buy?

Our top-rated vendor for each, based on trust scores, purity testing, and price.

Best FOXO4-DRI Vendor

Orbitrex Peptides
Orbitrex Peptides
9.0/10

$189.99(10mg)

Best MOTS-c Vendor

NextGen Health
NextGen Health
7.9/10

$80.00(40mg)

See all FOXO4-DRI vendorsSee all MOTS-c vendors

Where does this data come from?

We check vendor prices every day and pull in real purity test results from independent labs — not vendor claims. No vendor can pay to rank higher. See our full methodology.