FOXO4-DRI vs MOTS-c
Which should you choose? Here's what you need to know.
The short answer
FOXO4-DRI and MOTS-c are both metabolic / longevity peptides, but they work differently. A D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells. A mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism. Compare vendor pricing and availability below.
FOXO4-DRI
Metabolic / LongevityA D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells.
MOTS-c
Metabolic / LongevityA mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
FOXO4-DRI
MOTS-c
$99.99
Starting from
$29.99
$24.67
Avg. price per mg
$5.50
15
Vendors selling it
62
14 options
In stock now
75 options
9.0/10
Top trust score
9.0/10
0
Purity tests on file
0
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Best FOXO4-DRI Vendor
6.7/10
$255.00(15mg)
Best MOTS-c Vendor
7.8/10
$70.00(40mg)
Where does this data come from?
We check vendor prices every day and pull in real purity test results from independent labs — not vendor claims. No vendor can pay to rank higher. See our full methodology.