Retatrutide vs Tesofensine
Which should you choose? Here's what you need to know.
The short answer
Retatrutide and Tesofensine are both weight loss (glp-1) peptides, but they work differently. A next-generation triple agonist (GLP-1/GIP/glucagon) in clinical trials showing significant weight loss results. Considered the most promising obesity peptide in development. A triple monoamine reuptake inhibitor originally developed for neurological conditions, now studied for significant weight loss effects. Compare vendor pricing and availability below.
On 19 Sep 2026 Peptide Compare tracked 33 vendors selling Retatrutide, cheapest in stock $1.50 per mg at Step One, and 13 selling Tesofensine, cheapest $99.99 per mg at Umbrella Labs.
Retatrutide
Weight Loss (GLP-1)A next-generation triple agonist (GLP-1/GIP/glucagon) in clinical trials showing significant weight loss results. Considered the most promising obesity peptide in development.
Tesofensine
Weight Loss (GLP-1)A triple monoamine reuptake inhibitor originally developed for neurological conditions, now studied for significant weight loss effects.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 19, 2026.
Retatrutide
Tesofensine
$25.99
Starting from
$59.00
$9.88
Avg. price per mg
$325.95
33
Vendors selling it
13
112 options
In stock now
9 options
9.0/10
Top trust score
7.7/10
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.