Retatrutide vs Tirzepatide
Which should you choose? Here's what you need to know.
The short answer
Retatrutide adds a third receptor (glucagon) on top of what tirzepatide does. It's newer and less proven, but early trial data is impressive.
On 10 Oct 2026 Peptide Compare tracked 31 vendors selling Retatrutide, cheapest in stock $2.20 per mg at Modern Research, and 30 selling Tirzepatide, cheapest $1.76 per mg at Modern Research.
Retatrutide
Weight Loss (GLP-1)Retatrutide is a triple agonist — GLP-1, GIP, and glucagon — representing the newest generation. Phase 2 trials show it may outperform dual agonists for weight loss.
Choose Retatrutide if:
You want maximum weight loss potential and are okay with a less-proven compound.
Tirzepatide
Weight Loss (GLP-1)Tirzepatide is a dual GIP/GLP-1 agonist that's already FDA-approved as Mounjaro and Zepbound. It has strong clinical data showing up to 22.5% weight loss.
Choose Tirzepatide if:
You want an FDA-approved option with robust clinical trial data and real-world use.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Oct 10, 2026.
Retatrutide
Tirzepatide
$25.99
Starting from
$30.95
$10.03
Avg. price per mg
$9.04
31
Vendors selling it
30
98 options
In stock now
100 options
9.0/10
Top trust score
9.0/10
Ready to buy?
Our top-rated vendor for each, based on trust scores, purity testing, and price.
Some outbound links may earn us a commission. Vendors cannot pay to improve rankings.
Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.