Survodutide vs Tirzepatide
Which should you choose? Here's what you need to know.
The short answer
Both are dual agonists, but they pair GLP-1 with different second receptors. Tirzepatide (GIP) is FDA-approved with years of real-world use. Survodutide (glucagon) is still in trials, with notable liver-health results.
On 20 Sep 2026 Peptide Compare tracked 16 vendors selling Survodutide, cheapest in stock $7.50 per mg at Eros Peptides, and 32 selling Tirzepatide, cheapest $1.14 per mg at Step One.
Survodutide
Weight Loss (GLP-1)Survodutide pairs GLP-1 with glucagon, which may increase energy expenditure and directly reduce liver fat — its MASH trial results stand out in the class. It showed nearly 19% weight loss at 46 weeks and remains in Phase 3.
Choose Survodutide if:
The glucagon mechanism interests you — particularly its liver-fat effects — and you're comfortable with a compound still in trials.
Tirzepatide
Weight Loss (GLP-1)Tirzepatide pairs GLP-1 with GIP and is FDA-approved as Mounjaro and Zepbound. Clinical trials showed up to 22.5% weight loss, and it has the real-world track record survodutide doesn't yet have.
Choose Tirzepatide if:
You want an FDA-approved dual agonist with robust clinical data and wide real-world use.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 20, 2026.
Survodutide
Tirzepatide
$74.99
Starting from
$30.00
$13.16
Avg. price per mg
$8.89
16
Vendors selling it
32
14 options
In stock now
105 options
7.6/10
Top trust score
9.0/10
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Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.