Which should you choose? Here's what you need to know.
Tirzepatide is FDA-approved with strong weight loss evidence. 5-Amino-1MQ has an interesting mechanism (NNMT inhibition) but only mouse data — no human trials exist.
5-Amino-1MQ is an NNMT enzyme inhibitor that showed promise for reversing obesity in animal models. It works by increasing cellular energy expenditure rather than suppressing appetite.
Choose 5-Amino-1MQ if:
You want a non-appetite-suppressing approach to fat loss and are comfortable with an early-stage research compound.
Tirzepatide (Mounjaro/Zepbound) is a dual GIP/GLP-1 agonist with FDA approval, showing up to 22.5% weight loss in clinical trials across thousands of patients.
Choose Tirzepatide if:
You want proven, FDA-approved weight loss with extensive human safety data.
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Our top-rated vendor for each, based on trust scores, purity testing, and price.
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.