FOXO4-DRI vs NAD+
Which should you choose? Here's what you need to know.
The short answer
FOXO4-DRI and NAD+ are both metabolic / longevity peptides, but they work differently. A D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells. Nicotinamide Adenine Dinucleotide, a coenzyme essential for cellular energy production and DNA repair. Levels decline with age, driving longevity research interest. Compare vendor pricing and availability below.
On 20 Sep 2026 Peptide Compare tracked 28 vendors selling FOXO4-DRI, cheapest in stock $3.09 per mg at AMC Essentials, and 58 selling NAD+, cheapest $0.054 per mg at Step One.
FOXO4-DRI
Metabolic / LongevityA D-retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Studied as a potential senolytic agent for clearing aged cells.
NAD+
Metabolic / LongevityNicotinamide Adenine Dinucleotide, a coenzyme essential for cellular energy production and DNA repair. Levels decline with age, driving longevity research interest.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 20, 2026.
FOXO4-DRI
NAD+
$44.99
Starting from
$25.00
$16.95
Avg. price per mg
$0.31
28
Vendors selling it
58
23 options
In stock now
74 options
9.0/10
Top trust score
9.0/10
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.