Which should you choose? Here's what you need to know.
Both release growth hormone through ghrelin receptors, but ipamorelin is much more selective — it boosts GH without spiking hunger, cortisol, or prolactin. GHRP-6 gives a big appetite boost alongside GH release.
GHRP-6 is one of the earlier growth hormone releasing peptides. It's a potent GH secretagogue that also significantly stimulates appetite through ghrelin pathways. It raises cortisol and prolactin alongside growth hormone, which makes it less "clean" but useful for people who want the hunger boost.
Choose GHRP-6 if:
You actually want the appetite stimulation (e.g., you're underweight or in a bulking phase) and don't mind the cortisol and prolactin bump.
Ipamorelin is a newer, more selective growth hormone secretagogue. It releases GH at a comparable rate to GHRP-6 but without meaningfully raising cortisol, prolactin, or appetite. It's easier to use during cutting or body recomposition phases.
Choose Ipamorelin if:
You want growth hormone release with the fewest side effects — no hunger spikes, no cortisol or prolactin elevation.
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Our top-rated vendor for each, based on trust scores, purity testing, and price.
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Best GHRP-6 Vendor
$39.00(10mg)
Best Ipamorelin Vendor
$49.99(10mg)
We check vendor prices every day and pull in real purity test results from independent labs — not vendor claims. No vendor can pay to rank higher. See our full methodology.