Humanin vs MOTS-c
Which should you choose? Here's what you need to know.
The short answer
Humanin and MOTS-c are both metabolic / longevity peptides, but they work differently. A mitochondria-derived peptide with cytoprotective properties. Studied for neuroprotection, metabolic regulation, and cellular stress response. A mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism. Compare vendor pricing and availability below.
On 19 Sep 2026 Peptide Compare tracked 7 vendors selling Humanin, cheapest in stock $12.15 per mg at Oasis Labs, and 61 selling MOTS-c, cheapest $1.35 per mg at Step One.
Humanin
Metabolic / LongevityA mitochondria-derived peptide with cytoprotective properties. Studied for neuroprotection, metabolic regulation, and cellular stress response.
MOTS-c
Metabolic / LongevityA mitochondria-derived peptide that regulates metabolic homeostasis. Often called an "exercise mimetic" for its effects on AMPK activation and metabolism.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 19, 2026.
Humanin
MOTS-c
$46.00
Starting from
$22.00
$11.31
Avg. price per mg
$5.40
7
Vendors selling it
61
4 options
In stock now
83 options
6.6/10
Top trust score
9.0/10
Ready to buy?
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.