Which should you choose? Here's what you need to know.
Ipamorelin is a clean GH secretagogue that works through ghrelin receptors. Tesamorelin is a potent GHRH analog that's FDA-approved for belly fat reduction. Different receptors, often stacked together.
Ipamorelin selectively stimulates growth hormone release through ghrelin receptors without spiking cortisol, prolactin, or appetite. It's considered the cleanest GH peptide available.
Choose Ipamorelin if:
You want a clean, minimal-side-effect GH boost for recovery and anti-aging, especially if you're sensitive to hormonal side effects.
Tesamorelin is an FDA-approved GHRH analog with clinical data showing significant visceral fat reduction. It works through the GHRH receptor — a completely different pathway than ipamorelin.
Choose Tesamorelin if:
You're targeting visceral fat specifically, or you want an FDA-approved option with strong clinical evidence.
Ipamorelin + Tesamorelin is one of the most popular GH stacks. They hit different receptors (ghrelin vs GHRH), producing a synergistic GH pulse stronger than either alone.
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Our top-rated vendor for each, based on trust scores, purity testing, and price.
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.