MGF vs Sermorelin
Which should you choose? Here's what you need to know.
The short answer
MGF and Sermorelin are both growth hormone peptides, but they work differently. Mechano Growth Factor, a splice variant of IGF-1 produced in response to muscle damage. Studied for muscle repair and growth. A growth hormone releasing hormone (GHRH) analog commonly prescribed in anti-aging clinics. One of the most established peptides for GH optimization. Compare vendor pricing and availability below.
On 20 Sep 2026 Peptide Compare tracked 22 vendors selling MGF, cheapest in stock $11.80 per mg at Biotech Peptides, and 46 selling Sermorelin, cheapest $3.70 per mg at Step One.
MGF
Growth HormoneMechano Growth Factor, a splice variant of IGF-1 produced in response to muscle damage. Studied for muscle repair and growth.
Sermorelin
Growth HormoneA growth hormone releasing hormone (GHRH) analog commonly prescribed in anti-aging clinics. One of the most established peptides for GH optimization.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 20, 2026.
MGF
Sermorelin
$28.99
Starting from
$22.00
$18.48
Avg. price per mg
$8.60
22
Vendors selling it
46
19 options
In stock now
53 options
9.1/10
Top trust score
9.0/10
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.