Which should you choose? Here's what you need to know.
Semaglutide is the proven GLP-1 standard with FDA approval and millions of real-world doses. 5-Amino-1MQ is a novel NNMT inhibitor with promising mouse data but zero human trials.
5-Amino-1MQ inhibits the NNMT enzyme to increase cellular energy expenditure. In preclinical studies it reversed diet-induced obesity in mice with no adverse effects observed.
Choose 5-Amino-1MQ if:
You're interested in a non-GLP-1 mechanism and accept the risk of a compound with no human data.
Semaglutide (Ozempic/Wegovy) is the most widely prescribed GLP-1 agonist with FDA approval, 15-20% weight loss in trials, and cardiovascular benefits proven in the SELECT trial.
Choose Semaglutide if:
You want the most established weight loss peptide with the strongest evidence base.
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.
Our top-rated vendor for each, based on trust scores, purity testing, and price.
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.