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HomePeptides5-Amino-1MQ vs Semaglutide

5-Amino-1MQ vs Semaglutide

Which should you choose? Here's what you need to know.

The short answer

Semaglutide is the proven GLP-1 standard with FDA approval and millions of real-world doses. 5-Amino-1MQ is a novel NNMT inhibitor with promising mouse data but zero human trials.

5-Amino-1MQ

Weight Loss (GLP-1)

5-Amino-1MQ inhibits the NNMT enzyme to increase cellular energy expenditure. In preclinical studies it reversed diet-induced obesity in mice with no adverse effects observed.

Choose 5-Amino-1MQ if:

You're interested in a non-GLP-1 mechanism and accept the risk of a compound with no human data.

Semaglutide

Weight Loss (GLP-1)

Semaglutide (Ozempic/Wegovy) is the most widely prescribed GLP-1 agonist with FDA approval, 15-20% weight loss in trials, and cardiovascular benefits proven in the SELECT trial.

Choose Semaglutide if:

You want the most established weight loss peptide with the strongest evidence base.

Price & availability

Once you've decided which peptide fits your needs, here's how they compare on price and vendor options.

5-Amino-1MQ
Semaglutide
$19.95
Starting from
$20.00
$4.32
Avg. price per mg
$22.28
45
Vendors selling it
36
60 options
In stock now
77 options
9.0/10
Top trust score
8.7/10

Ready to buy?

Our top-rated vendor for each, based on trust scores, purity testing, and price.

Best 5-Amino-1MQ Vendor

Eros Peptides
Eros Peptides
6.9/10

$49.99(50mg)

Check Price

Best Semaglutide Vendor

Polaris Peptides
Polaris Peptides
7.3/10

$165.00(20mg)

Check Price
See all 5-Amino-1MQ vendorsSee all Semaglutide vendors

Where does this data come from?

We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.