Gonadorelin vs PT-141
Which should you choose? Here's what you need to know.
The short answer
Gonadorelin and PT-141 are both sexual health peptides, but they work differently. A synthetic form of gonadotropin-releasing hormone (GnRH) used to stimulate LH and FSH production. Used clinically alongside TRT to maintain fertility. A melanocortin receptor agonist FDA-approved as Vyleesi for hypoactive sexual desire disorder. Works through the nervous system rather than the vascular system. Compare vendor pricing and availability below.
On 20 Sep 2026 Peptide Compare tracked 11 vendors selling Gonadorelin, cheapest in stock $6.54 per mg at Paramount Peptides, and 52 selling PT-141, cheapest $2.00 per mg at Step One.
Gonadorelin
Sexual HealthA synthetic form of gonadotropin-releasing hormone (GnRH) used to stimulate LH and FSH production. Used clinically alongside TRT to maintain fertility.
PT-141
Sexual HealthA melanocortin receptor agonist FDA-approved as Vyleesi for hypoactive sexual desire disorder. Works through the nervous system rather than the vascular system.
Price & availability
Once you've decided which peptide fits your needs, here's how they compare on price and vendor options. Prices verified Sep 20, 2026.
Gonadorelin
PT-141
$20.00
Starting from
$20.00
$30.77
Avg. price per mg
$5.86
11
Vendors selling it
52
11 options
In stock now
50 options
7.6/10
Top trust score
9.0/10
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Where does this data come from?
We re-check vendor prices continuously and score vendors on Finnrick blind-test results — samples bought anonymously and sent to a lab, not vendor claims. No vendor can pay to rank higher. See our full methodology.