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Home/Metabolic / Longevity/AICAR

AICAR

An AMPK activator studied as an exercise mimic in mice. A nucleoside, not a peptide; its infused form failed a large heart-surgery trial.

Peptide Compare tracked 8 vendors selling AICAR on 10 Oct 2026. The cheapest in-stock 50 mg vial is $0.760 per mg at Ruo Bio, 36% under the $1.18 median. Prices are scraped from vendor sites; trust scores come from Finnrick blind tests.

Some outbound links may earn us a commission. Vendors cannot pay to improve rankings.

Best value right now · 50 mg
Ruo Bio
Ruo Bio
IN STOCKUNTESTED
Per mg$0.76036% under the $1.18 median
Vial price$38.0050 mg · verified Oct 10
Go to Ruo Bio↗
Avg per mg · 50 mgAverage cost per mg · 50 mg vials · past 3 months
$1.12−3.4%
Ranged $1.12 – $1.16 across 8 vendors
AVERAGECHEAPEST
TODAY · Oct 10$1.12$0.760
May 1Aug 18Sep 3Sep 19Oct 10
Vial size

Compare 7 vendors · 50 mg

Across all sizes, verified in-stock listings run $38.00 to $59.99 from 3 vendors.

VendorStock
01
Ruo Bio
Ruo BioBest value
untested
$38.00
$0.76036% UNDER MED
In stock
Buy ↗
01
Ruo Bio
Ruo BioUNTESTED
$0.760$38.00
Buy
02
Ion Peptide
Ion Peptide
untested
$59.00
$1.18AT MEDIAN
In stock
Buy ↗
02
Ion Peptide
Ion PeptideUNTESTED
$1.18$59.00
Buy
03
NorthWest Peptides
NorthWest Peptides
untested
$59.99
$1.202% OVER MED
In stock
Buy ↗
03
NorthWest Peptides
NorthWest PeptidesUNTESTED
$1.20$59.99
Buy
04
Behemoth Labz
Behemoth Labz
untested
$55.96
$1.125% UNDER MED
Out
04
Behemoth Labz
Behemoth LabzUNTESTED · OUT
$1.12$55.96
05
Biotech Peptides
Biotech Peptides
untested
$56.00
$1.125% UNDER MED
Out
05
Biotech Peptides
Biotech PeptidesUNTESTED · OUT
$1.12$56.00
06
Peptira
Peptira
untested
$59.00
$1.18AT MEDIAN
Out18d
06
Peptira
PeptiraUNTESTED · OUT
$1.18$59.00
07
Peptide Sciences
Peptide Sciences
6.6
$65.00
$1.3010% OVER MED
Out65d
07
Peptide Sciences
Peptide SciencesTRUST 6.6 · OUT
$1.30$65.00

AICAR prices verified Oct 10, 2026

$0.760/mgRuo Bio · $38.00
Buy best price↗

See how AICAR moved against the rest of the catalogue in the Peptide Price Index: median price per mg now versus 30 and 90 days ago, every tracked peptide, with a CSV.

AICAR price by vial size

Lowest verified in-stock price for AICAR at each vial size
Vial sizeLowest per mgVial priceVendorVendors carrying it
50 mg$0.760$38.00Ruo Bio7 vendors carry it7
Othernone verified in stock1 vendor carries it1

Verified 10 Oct 2026. Lowest figures are in-stock listings checked within the last week, with any coupon applied; a size with none says so.

Price movement · 30 days
0%median per mg, all sizes
Cheapest ever recorded: $0.760/mg on Aug 7. Today matches it.
Purity coverage
2 of 8vendors lab-tested
Method →
Track AICAR priceReconstitution calculator

See our top-ranked AICAR vendors

Ranked by Finnrick trust score, independent lab testing, and price.

Best vendors

Compare AICAR head-to-head

  • AICAR vs SS-31
  • AICAR vs MOTS-c
  • AICAR vs Epithalon
  • AICAR vs NAD+
  • AICAR vs FOXO4-DRI
  • AICAR vs SLU-PP-332
All peptide comparisons
Quick Summary

An AMP analogue (5-aminoimidazole-4-carboxamide ribonucleoside) that activates the energy sensor AMPK. Its infused form, acadesine, failed a large cardiac-surgery trial. It is a nucleoside, not a peptide, and no regulator has approved it. Available from 8 vendors, priced from $38.00 to $89.99.

Research: In sedentary mice, four weeks of AICAR alone raised treadmill running endurance by 44% (Narkar et al, Cell 2008;134(3):405-415, PMID 18674809). The only large human trial tested acadesine, its nucleoside form, in 3,080 patients having bypass surgery and was stopped for futility: the composite of death, stroke or severe left-ventricular dysfunction occurred in 5.1% on acadesine and 5.0% on placebo (RED-CABG, Newman et al, JAMA 2012;308(2):157-164, PMID 22782417). The mouse endurance result has never been tested in people.
Side effects: No adverse event table for AICAR as sold has been published, RED-CABG reported no difference from placebo in its main efficacy and safety end points for infused acadesine
Not approvedNo Drugs@FDA record for AICAR or acadesine. Named on the WADA 2026 Prohibited List under S4.4 AMPK activators, alongside BAM15 and MOTS-c.
  • 4 of 8 vendors currently have it in stock
  • Highest-rated vendor: Peptidology (7.6 Finnrick score)
  • Most common vial size: 50mg
  • Category: Metabolic / Longevity — Longevity, mitochondrial, and metabolic peptides

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